The main focus of the Core Bioinformatics team is undertaking software development and system administration of our in-house solutions for data management and visualisation. These include MISO, TGAC's Lab Information Management System (LIMS), a bespoke platform for recording metadata for NGS experiments, and the TGAC Browser, a novel web-based performance-oriented browsing platform for high-throughput NGS genomic datasets. These tools are open-source, an ethos the team firmly believes in, and we aim to promote and disseminate our work to the community through online information resources, meetings, workshops and training courses.

As well as software design and development, the team regularly submits sequencing data to public repositories as part of TGAC's core remit. These data comprise raw reads, preliminary contigs, draft assemblies and annotation features.

Supporting our core facility at TGAC is a cornerstone of our team’s activities. We manage installations of our productivity and bioinformatics applications that benefit colleagues and external collaborators, such as genome browsers, information portals and the TGAC website.

• Xingdong Bian - Scientific Programmer
• Anil Thanki - Scientific Programmer

• Collaborations for extending and supporting MISO
• Fine-grained data management through data grids, such as iRODS
• Novel visualisations of project information and datasets

• Posters:
• Davey R, Bian X, Holland R, Caccamo M. Poster: MISO: an open-­source LIMS for small-­to-­large sequencing centres, Intelligent System for Molecular Biology Conference, Boston July 2010;
• Davey R, Bian X, Caccamo M. Poster: MISO: an open-­source LIMS for small-­to-­large sequencing centres, UK Next Gen Sequencing Meeting, University of Nottingham Aug 2011;
• Davey R, Bian X, Thanki A, Caccamo M. Poster: MISO: an open-­source LIMS for small­-to-­large sequencing centres, Advances in Genome Biology and Technology (AGBT), Marco Island Florida Feb 2012.