We are pleased to announce the launch of our free open source LIMS system, MISO (Managing Information for
Sequencing Operations). The system has been developed and designed to track next-generation sequencing experiments. Recently presented at the 2012 ISMB conference in Long Beach, MISO is receiving interest and positive comments via personal communication and social networking.
Developed using fully open source technology, MISO is able to record sequencing metadata based on a wide array of NGS sequencing platforms (i.e. Illumina GA, HiSeq and MiSeq, Roche 454, AB SOLiD and PacBio RS), and public repository data submission schemas (i.e. the Sequence Read Archive at the EBI). MISO has features common to both bespoke and proprietary LIMS such as secure authentication, fine-grained access control, simple sample and library preparation workflows, barcode tracking and reporting. Other features of MISO include high-performance compute access to bespoke bioinformatics pipelines, novel data visualisation strategies, user alerting, and run progress notifications.
MISO is a modular system from top to bottom, allowing core functionality to be reused and swapped out for elements
developed by the community. In this way, we are currently working on new plugin features which will enable MISO to be extendable, making it easier for the community to contribute more features.
MISO comes with a user-friendly interface which has been designed specifically for use by NGS lab technicians, but can also be queried programmatically, meaning helpful web services can be developed on top of MISO to provide remote custom reporting and interoperability with other systems.
We are currently working on automated data delivery solutions to user-configured submission endpoints, to make it even
easier to submit sequencing data to public repositories.
To stay up to date with the latest MISO updates, please follow us on Twitter: @misolims.
If you wish to try a demo version of MISO please visit http://miso-demo.tgac.ac.uk using “misodemo” as both the username and password.